Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574422 | 0.99 | EGFR (0.47) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL889415 | 0.86 | EGFR (0.51) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL16079758 | 0.86 | ALDH1A1 (0.60) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL39437 | 0.82 | EGFR (0.48) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL25255502 | 0.81 | EGFR (0.69) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL10044900 | 0.80 | CA12 (0.48) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7826321 | 0.80 | HDAC4 (0.58) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL19114816 | 0.79 | MEN1 (0.60) | EGFRMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1685962 | 0.79 | ALDH1A1 (0.65) | MEN1KMT2ANPC1ALDH1A1POLB | |
| SCHEMBL39159 | 0.79 | EGFR (0.70) | EGFRMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035001-A2 | STABLE LAQUINIMOD PREPARATIONS | Teva Pharmaceutical Industries Limited (IL) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146248-A2 | STABLE LAQUINIMOD PREPARATIONS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-12-21 | — | — | WO | disclosed |