SCHEMBL425349

SCHEMBL425349

CN(C)CCS(N)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27689607 0.97 ALDH1A1 (0.36)
SCHEMBL3115464 0.83 ALDH1A1 (0.43)
SCHEMBL13439770 0.82 LTA4H (0.44)
SCHEMBL14932176 0.81 ALDH1A1 (0.48)
Acrylamide SCHEMBL28091591 0.81 ALDH1A1 (0.42)
SCHEMBL28238302 0.79 ALDH1A1 (0.52)
Acrylamide SCHEMBL28081090 0.79 ALDH1A1 (0.41)
SCHEMBL23978215 0.78
SCHEMBL6493234 0.76 CA1 (0.32)
SCHEMBL6494972 0.76 LTA4H (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936496-B Heterocyclic compounds useful as medicaments 马萨里克大学 2023-12-29 CN claimed
US-11498920-B2 4-(1H-imidazol-5-yl)-1H-pyrrolo[2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors MASARYKOVA UNIVERZITA (CZ) 2022-11-15 US claimed
EP-3774795-B1 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS UNIV MASARYKOVA (CZ) 2022-03-16 EP claimed
EP-3774795-A1 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS Masarykova Univerzita (CZ) 2021-02-17 EP claimed
US-20210040086-A1 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS MASARYKOVA UNIVERZITA (CZ) 2021-02-11 US claimed
CN-111936496-A Use of 4- (1H-imidazol-5-yl) -1H-pyrrolo [2,3-B ] pyridine for the treatment of leukemias, lymphomas and solid tumors 马萨里克大学 2020-11-13 CN claimed
WO-2019185631-A1 4—(1H— IMIDAZOL— 5— YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS MASARYKOVA UNIVERZITA (CZ) 2019-10-03 WO claimed
US-20190002460-A1 SMALL MOLECULE INHIBITORS OF EGFR AND PI3K THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2019-01-03 US claimed
US-20100063049-A1 2-CARBOCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHBITION OF CELL PROLIFERATION ASTRAZENECA AB (SE) 2010-03-11 US claimed
CN-101454312-A 2-Carbocyclic amino-4-imidazolyl pyrimidines as inhibitors of cell proliferation ASTRAZENECA AB (SE) 2009-06-10 CN claimed
US-5084453-A Antibiotics, bactericides BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-01-28 US claimed
US-20260116881-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2025111582-A1 AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D GENENTECH, INC. (US) 2025-05-30 WO disclosed
WO-2025081019-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
CN-1324344-A N- (2-aryl-propionyl) -sulfonamides and pharmaceutical compositions containing them DOMPE SPA (IT) 2001-11-28 CN disclosed
EP-1123276-A1 N-(2-ARYL-PROPIONYL)-SULFONAMIDES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM Dompe' S.P.A. (IT) 2001-08-16 EP disclosed
WO-2000024710-A1 N-(2-ARYL-PROPIONYL)-SULFONAMIDES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM DOMPE' S.P.A. (IT) 2000-05-04 WO disclosed
EP-0904265-A1 PREPARATION OF BIS(FLUOROALKYLENESULFONYL)IMIDES AND (FLUOROALKYLSULFONYL) (FLUOROSULFONYL)IMIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-31 EP disclosed
WO-1997023448-A1 PREPARATION OF BIS(FLUOROALKYLENESULFONYL)IMIDES AND (FLUOROALKYLSULFONYL) (FLUOROSULFONYL)IMIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-07-03 WO disclosed