Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253702 | 1.00 | ALDH1A1 (0.60) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL4253299 | 0.94 | ALDH1A1 (0.67) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL4253302 | 0.94 | ALDH1A1 (0.67) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL6587578 | 0.84 | TAAR1 (0.59) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL7664431 | 0.84 | ALDH1A1 (0.58) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL7664429 | 0.84 | ALDH1A1 (0.58) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL4254637 | 0.82 | G6PC1 (0.51) | ALDH1A1G6PC1CYP11B2TAAR1MAPT | |
| SCHEMBL4254642 | 0.82 | G6PC1 (0.51) | ALDH1A1G6PC1CYP11B2TAAR1MAPT | |
| SCHEMBL7667155 | 0.82 | G6PC1 (0.60) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 | |
| SCHEMBL4900404 | 0.82 | ALDH1A1 (0.56) | ALDH1A1G6PC1CYP11B2CYP11B1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | claimed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | claimed |
| US-8268933-B2 | Polymers functionalized with polyimine compounds | BRIDGESTONE CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20090171035-A1 | POLYMERS FUNCTIONALIZED WITH POLYIMINE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-07-02 | — | — | US | disclosed |