Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689784 | 0.83 | CA12 (0.67) | SCN2ACA12CA9CA1CA2 | |
| SCHEMBL11724682 | 0.82 | ALDH1A1 (0.53) | ESR1CA12KMT2AALDH1A1MAPT | |
| SCHEMBL11724665 | 0.82 | KMT2A (0.52) | SCN2AESR1CA12MEN1KMT2A | |
| SCHEMBL4255804 | 0.80 | ESR1 (0.64) | SCN2AESR1CA12CA9CA1 | |
| SCHEMBL28911652 | 0.80 | CA12 (0.70) | SCN2ACA12CA9CA1CA2 | |
| SCHEMBL10013240 | 0.79 | ALDH1A1 (0.65) | SCN2AESR1CA9CA1MEN1 | |
| SCHEMBL12639212 | 0.79 | ESR1 (0.72) | ESR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL17326265 | 0.78 | SCN2A (0.67) | SCN2AESR1CA12CA9CA1 | |
| SCHEMBL4251148 | 0.77 | NPC1 (0.58) | ESR1CA9CA1CA2MEN1 | |
| SCHEMBL4258439 | 0.77 | ESR1 (0.61) | ESR1CA12CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054653-A2 | ISOINDOLONES WITH HIGH BINDING AFFINITY TO BETA-AMYLOID AGGREGATES AND FIBRILS, AND ITS USE AND PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-04-30 | — | — | WO | disclosed |