Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8564648 | 0.99 | ACACB (0.54) | ACACBHTR2C | |
| SCHEMBL20480419 | 0.86 | ACACB (0.54) | ACACBHTR2C | |
| SCHEMBL3791716 | 0.84 | ACACB (0.41) | ACACBHTR2C | |
| Hydrochloric Acid SCHEMBL3712745 | 0.83 | ACACB (0.41) | ACACBHTR2C | |
| SCHEMBL3709050 | 0.82 | HTR2C (0.45) | ACACBHTR2C | |
| SCHEMBL13636479 | 0.81 | HDAC3 (0.41) | ACACBHTR2C | |
| SCHEMBL4511692 | 0.81 | ACACB (0.40) | ACACB | |
| SCHEMBL3792752 | 0.80 | HDAC3 (0.40) | ACACBHTR2C | |
| SCHEMBL3708949 | 0.80 | HDAC3 (0.43) | ACACBHTR2C | |
| SCHEMBL1590677 | 0.80 | HTR2C (0.45) | ACACBHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | CORBETT JEFFREY WAYNE | 2009-10-29 | — | — | US | disclosed |
| EP-2097420-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | Pfizer Products Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008065508-A1 | SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270435-A1 | Spiroketone Acetyl-CoA Carboxylase Inhibitors | ACACA, PC, ACACB | ACACB 3/4885HTR2C 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.