Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337428 | 0.95 | MEN1 (0.76) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1986154 | 0.88 | KMT2A (0.74) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9423144 | 0.88 | MAPT (1.00) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL10943066 | 0.86 | KMT2A (0.94) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29396789 | 0.86 | KMT2A (1.00) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL1337652 | 0.86 | MAPT (0.77) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31254103 | 0.85 | KMT2A (0.87) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28342284 | 0.85 | KMT2A (0.87) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL30862297 | 0.85 | RXFP1 (0.94) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL4251968 | 0.85 | RXFP1 (0.94) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620122-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1996-03-13 | — | — | EP | claimed |
| US-5446010-A | Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability | NEW OJI PAPER CO., LTD. (JP) | 1995-08-29 | — | — | US | claimed |
| EP-0620122-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-10-19 | — | — | EP | claimed |
| US-20170166555-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | NOVOGEN LIMITED (AU) | 2017-06-15 | — | — | US | disclosed |
| CN-105916841-A | Functionalised and substituted indoles as anti-cancer agents | 诺沃根公司 | 2016-08-31 | — | — | CN | disclosed |
| US-7541459-B2 | Method of producing amide compound | FUJIFILM CORPORATION (JP) | 2009-06-02 | — | — | US | disclosed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-5728835-A | HYPOTENSIVE AGENTS; ANTIISCHEMIC AGENTS | TOA EIYO, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0620122-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5446010-A | Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability | NEW OJI PAPER CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0661266-A1 | Substituted cyclic amine compounds as 5HT2 antagonists | TOA EIYO LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0620122-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166555-A1 | FUNCTIONALISED AND SUBSTITUTED INDOLES AS ANTI-CANCER AGENTS | TPM3, TPM4, TNNI3 | MEN1 3325/4885KMT2A 2215/4885MAPT 2167/4885 |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | GABBR1, GABBR2, CHRM2 | MEN1 1233/4885KMT2A 632/4885MAPT 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.