Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254301 | 1.00 | GLS (0.47) | GLSCTSKAKT1CTSSATM | |
| SCHEMBL28299509 | 0.88 | CTSK (0.47) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL506117 | 0.88 | CTSK (0.47) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL30940056 | 0.87 | CTSK (0.46) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL29228867 | 0.87 | CTSK (0.46) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL30458149 | 0.87 | CTSK (0.46) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL14395967 | 0.86 | CTSK (0.47) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL14987513 | 0.86 | GLS (0.51) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL14987521 | 0.86 | GLS (0.49) | GLSCTSKCTSSATMCTSB | |
| SCHEMBL5913936 | 0.85 | GLS (0.46) | GLSCTSKCTSSATMCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053277-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-30 | — | — | WO | disclosed |