Hexestrol Diphosphate

Hexestrol Diphosphate

SCHEMBL4254504

CC[C@H](c1ccc(OP(=O)(O)O)cc1)[C@@H](CC)c1ccc(OP(=O)(O)O)cc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.61
ESR1 P03372 2/20 0.54
HIF1A Q16665 1/20 0.54
CYP2C19 P33261 2/20 0.48
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.48
PGR P06401 1/20 0.48
CHRM2 P08172 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
AR P10275 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
CHRM1 P11229 1/20 0.48
CYP2C9 P11712 1/20 0.48
ALOX15 P16050 1/20 0.48
DRD1 P21728 1/20 0.48
TBXA2R P21731 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexestrol Diphosphate SCHEMBL62206 1.00 BLM (0.61) BLMESR1HIF1ACYP2C19LMNA
SCHEMBL209725 0.93 ESR1 (0.61) BLMESR1HIF1ACYP2C19LMNA
SCHEMBL209724 0.93 ESR1 (0.61) BLMESR1HIF1ACYP2C19LMNA
Diethylstilbestrol Diphosphate SCHEMBL8153893 0.85 BLM (0.70) BLMESR1HIF1ACYP2C19LMNA
SCHEMBL12716935 0.84 BLM (0.54) BLMCYP2C19MAPTTDP1SRC
SCHEMBL4254509 0.81 ESR1 (0.54) BLMESR1HIF1ACYP2C19LMNA
SCHEMBL223266 0.79 SRC (0.54) BLMLMNASRCCA1CA2
SCHEMBL27342545 0.77 SRC (0.52) BLMLMNASRCCA1CA2
SCHEMBL329313 0.77 SRC (0.75) BLMCYP2C19CYP3A4SRCCA1
SCHEMBL924938 0.76 SRC (0.56) BLMCYP2C19SRCCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186486-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION BAYLOR COLLEGE OF MEDICINE (US) 2025-06-12 US disclosed
WO-2025068966-A2 SYNERGISTIC DENTIFRICE (ORAL) COMPOSITION, FORMULATION AND PREPARATION METHOD AND APPLICATION THEREOF RAI BALWANT (IN) 2025-04-03 WO disclosed
EP-4493166-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION Baylor College of Medicine (US) 2025-01-22 EP disclosed
WO-2023177870-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION BAYLOR COLLEGE OF MEDICINE (US) 2023-09-21 WO disclosed
CN-113774106-B Method for detecting genotoxicity by utilizing 3D liver cell in-vitro micronucleus cytology 上海益诺思生物技术股份有限公司 2023-08-15 CN disclosed
CN-111909097-B Method for purifying bendamustine hydrochloride 南京力成药业有限公司 2022-04-05 CN disclosed
US-20160008376-A1 Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders BIOCOPEA LIMITED (GB) 2016-01-14 US disclosed
WO-2016005599-A1 COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS BIOCOPEA LIMITED (GB) 2016-01-14 WO disclosed
CN-103492590-A Circulating biomarkers CARIS LIFE SCIENCES LUXEMBOURG HOLDINGS S A R L 2014-01-01 CN disclosed
US-20090048667-A1 Controlled Drug-Release Composition and Drug-Releasable Medical Device TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2009-02-19 US disclosed
US-5330767-A Sustained release microcapsule TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-07-19 US disclosed
EP-0190833-B1 METHOD FOR PRODUCING MICROCAPSULE Takeda Chemical Industries, Ltd. (JP) 1991-03-27 EP disclosed
US-4954298-A Method for producing microcapsule TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-04 US disclosed
EP-0190833-A2 Method for producing microcapsule Takeda Chemical Industries, Ltd. (JP) 1986-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048667-A1 Controlled Drug-Release Composition and Drug-Releasable Medical Device LDLR, SRR, PLAUR BLM 1668/4885ESR1 3645/4885HIF1A 3259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.