SCHEMBL425466

SCHEMBL425466

CNC(=O)CN(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29494595 0.97
SCHEMBL13793800 0.83 ALDH1A1 (0.34)
SCHEMBL13663235 0.83 MCL1 (0.33)
SCHEMBL13567026 0.82 MCL1 (0.40)
SCHEMBL17173842 0.78
SCHEMBL14980959 0.78
SCHEMBL16384464 0.78
SCHEMBL25933209 0.78
SCHEMBL8363255 0.78 CA12 (0.43)
SCHEMBL19212987 0.78 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819176-B 4-azaindole compounds 百时美施贵宝公司 2023-12-15 CN claimed
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US claimed
EP-1113806-B1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA PTY LTD (AU) 2007-09-05 EP claimed
EP-0765357-B9 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-08-16 EP claimed
EP-0927217-B1 ANGIOGENIC INHIBITORY COMPOUNDS STARPHARMA PTY LTD (AU) 2006-05-03 EP claimed
EP-0765357-B8 ANTIVIRAL DENDRIMERS STARPHARMA PTY LTD (AU) 2006-03-08 EP claimed
EP-1212318-B1 SUBSTITUTED INDOLINONES AS TYROSINE KINASE INHIBITORS BOEHRINGER INGELHEIM PHARMA (DE) 2006-01-25 EP claimed
EP-0765357-B1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 2005-12-14 EP claimed
US-20050009898-A1 New substituted indolinones, their manufacture and their use as medicaments BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2005-01-13 US claimed
US-6794395-B1 Substituted indolinones, their manufacture and their use as medicaments BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-09-21 US claimed
EP-1113805-A1 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS Starpharma Limited (AU) 2001-07-11 EP claimed
EP-1113806-A1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS Starpharma Limited (AU) 2001-07-11 EP claimed
US-6190650-B1 FOR PROPHYLAXIS AND THERAPY OF VIRAL DISEASES IN HUMANS AND ANIMALS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 2001-02-20 US claimed
WO-2000015240-A1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA LIMITED (AU) 2000-03-23 WO claimed
WO-2000015239-A1 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LIMITED (AU) 2000-03-23 WO claimed
EP-0927217-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1999-07-07 EP claimed
WO-1998003573-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1998-01-29 WO claimed
EP-0765357-A4 ANTIVIRAL DENDRIMERS BIOMOLECULAR RES INST LTD (AU) 1997-07-30 EP claimed
EP-0765357-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1997-04-02 EP claimed
WO-1995034595-A1 ANTIVIRAL DENDRIMERS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1995-12-21 WO claimed