SCHEMBL4254685

SCHEMBL4254685

CCOC(=O)/C=C(/Br)C(=O)OCC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.63
HCAR2 Q8TDS4 1/20 0.43
GLO1 Q04760 1/20 0.42
ALDH1A1 P00352 5/20 0.39
TRPA1 O75762 1/20 0.38
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
S1PR4 O95977 1/20 0.37
S1PR1 P21453 1/20 0.37
MAPK1 P28482 1/20 0.37
TSHR P16473 1/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247638 1.00 NPSR1 (0.63) NPSR1HCAR2GLO1ALDH1A1TRPA1
SCHEMBL4247641 1.00 NPSR1 (0.63) NPSR1HCAR2GLO1ALDH1A1TRPA1
SCHEMBL1321694 0.80 NPSR1 (0.65) NPSR1HCAR2GLO1ALDH1A1TRPA1
SCHEMBL5667523 0.80 NPSR1 (0.65) NPSR1HCAR2GLO1ALDH1A1TRPA1
SCHEMBL5612231 0.80 NPSR1 (0.65) NPSR1HCAR2GLO1ALDH1A1TRPA1
SCHEMBL8733229 0.79
SCHEMBL5087405 0.79
SCHEMBL6002149 0.79 HCAR2 (0.47) NPSR1HCAR2ALDH1A1SMN1; SMN2LMNA
SCHEMBL4246454 0.79 HCAR2 (0.47) NPSR1HCAR2ALDH1A1SMN1; SMN2LMNA
SCHEMBL4246450 0.79 HCAR2 (0.47) NPSR1HCAR2ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111840113-B Antibacterial skin cleaning lotion 百草堂(湖北)制药有限公司 2022-09-06 CN claimed
CN-112042664-B Mildew-proof antibacterial agent 广州古神生物科技有限公司 2022-06-10 CN claimed
CN-111957266-B Antibacterial surfactant and antibacterial and bacteriostatic application thereof in daily chemical products 广州古神生物科技有限公司 2022-06-07 CN claimed
EP-2295438-B2 PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND TOSOH CORP (JP) 2025-03-26 EP disclosed
CN-111840113-B Antibacterial skin cleaning lotion 百草堂(湖北)制药有限公司 2022-09-06 CN disclosed
CN-112042664-B Mildew-proof antibacterial agent 广州古神生物科技有限公司 2022-06-10 CN disclosed
CN-111957266-B Antibacterial surfactant and antibacterial and bacteriostatic application thereof in daily chemical products 广州古神生物科技有限公司 2022-06-07 CN disclosed
CN-105837714-B The manufacturing method of solid catalyst component for olefin polymerization, the manufacturing method of polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2018-07-20 CN disclosed
CN-104470953-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2017-11-14 CN disclosed
US-20160355616-A1 Polyvinyl Pyrrolidone analog Polymers LOGIN ROBERT BERNARD (US) 2016-12-08 US disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
CN-101203142-A Aromatic amides and ureas and their uses as sweet and/or delicate flavor modifiers, flavouring agents and taste enhancers SENOMYX INC (US) 2008-06-18 CN disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NPSR1 937/4885HCAR2 354/4885GLO1 3348/4885
US-20160355616-A1 Polyvinyl Pyrrolidone analog Polymers PBRM1, HMBS, BPGM NPSR1 918/4885HCAR2 1743/4885GLO1 784/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NPSR1 937/4885HCAR2 354/4885GLO1 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.