Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.79 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibutyl Phthalate SCHEMBL10731020 | 1.00 | ALDH1A1 (0.79) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL1943177 | 0.98 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL9298568 | 0.98 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Dibutyl Phthalate SCHEMBL8962381 | 0.97 | TSHR (0.78) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Dibutyl Sebacate SCHEMBL5445113 | 0.97 | TSHR (0.78) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| SCHEMBL10355198 | 0.97 | TSHR (0.78) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Dibutylsuccinate SCHEMBL8962345 | 0.95 | ALDH1A1 (0.82) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Dibutyl Phthalate SCHEMBL11523616 | 0.95 | TSHR (0.81) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Adipic Acid SCHEMBL10398044 | 0.93 | ALDH1A1 (0.73) | ALDH1A1TSHRLMNAMAPK1CYP3A4 | |
| Dibutyl Sebacate SCHEMBL7768874 | 0.91 | TSHR (0.69) | ALDH1A1TSHRLMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8784989-B2 | Sealant compositions having a novel plasticizer | EASTMAN CHEMICAL COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| EP-2057243-B1 | SEALANT COMPOSITIONS HAVING A NOVEL PLASTICIZER | EASTMAN CHEM CO (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-2057243-A1 | SEALANT COMPOSITIONS HAVING A NOVEL PLASTICIZER | Eastman Chemical Company (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20080057317-A1 | Self-curing composition: acrylic polymers, polyurethanes or polyureas, and silane-modified polymers, a mineral filler, and a C4 to C8 alkyl terephthalate; fill in cracks, water tight, paintable | EASTMAN CHEMICAL COMPANY (US) | 2008-03-06 | — | — | US | disclosed |
| WO-2008027463-A1 | SEALANT COMPOSITIONS HAVING A NOVEL PLASTICIZER | EASTMAN CHEMICAL COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |