Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibutyl Phthalate SCHEMBL8962381 | 1.00 | TSHR (0.78) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28783681 | 0.98 | TSHR (0.77) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| Dibutyl Phthalate SCHEMBL11523616 | 0.98 | TSHR (0.81) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28236934 | 0.97 | ALDH1A1 (0.79) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL4255174 | 0.97 | ALDH1A1 (0.79) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| Dibutyl Phthalate SCHEMBL10731020 | 0.97 | ALDH1A1 (0.79) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL10355198 | 0.97 | TSHR (0.78) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL28878375 | 0.95 | ALDH1A1 (0.82) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL1943177 | 0.95 | ALDH1A1 (0.82) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9298568 | 0.95 | ALDH1A1 (0.82) | TSHRTDP1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070116757-A1 | Methylene Blue Derivatives | COLLEGIUM PHARMACEUTICAL, INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070116757-A1 | Methylene Blue Derivatives | ACMSD, SI, HTR2B | TSHR 4306/4885TDP1 4600/4885L3MBTL1 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.