Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259414 | 0.89 | CSNK2A2 (0.46) | L3MBTL1CSNK2A2CSNK2A1CYP1A2CYP2C19 | |
| SCHEMBL13621662 | 0.84 | CSNK2A2 (0.42) | L3MBTL1CSNK2A2CSNK2A1CYP1A2CYP2C19 | |
| SCHEMBL13609557 | 0.84 | CYP1A2 (0.64) | L3MBTL1CYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL13609506 | 0.82 | CYP1A2 (0.49) | CSNK2A2CSNK2A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL9386919 | 0.82 | GAA (0.57) | L3MBTL1CSNK2A2CSNK2A1CYP1A2CYP2C19 | |
| SCHEMBL9386914 | 0.82 | GAA (0.57) | L3MBTL1CSNK2A2CSNK2A1CYP1A2CYP2C19 | |
| SCHEMBL4256594 | 0.81 | CYP1A2 (0.48) | CYP1A2CYP2C19RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4255395 | 0.81 | MAPK1 (0.49) | CSNK2A2CSNK2A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6922805 | 0.81 | CSNK2A2 (0.45) | CSNK2A2CSNK2A1CYP1A2CYP2C19RAB9A | |
| SCHEMBL4256337 | 0.80 | CSNK2A2 (0.46) | CSNK2A2CSNK2A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281142-A1 | THIAZOLE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20090281142-A1 | THIAZOLE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1921074-A1 | THIAZOLE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | GK, GCKR, AK2 | L3MBTL1 2114/4885CSNK2A2 1200/4885CSNK2A1 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.