Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609562 | 0.88 | MAPK1 (0.42) | CSNK2A2CSNK2A1MEN1KMT2ATSHR | |
| SCHEMBL4259417 | 0.87 | CSNK2A2 (0.44) | CSNK2A2CSNK2A1MEN1KMT2ACASP1 | |
| SCHEMBL13609547 | 0.85 | CSNK2A2 (0.43) | CSNK2A2CSNK2A1MEN1KMT2ACASP1 | |
| SCHEMBL13609558 | 0.84 | CSNK2A2 (0.41) | CSNK2A2CSNK2A1MEN1KMT2ACASP1 | |
| SCHEMBL13609563 | 0.83 | CSNK2A2 (0.40) | CSNK2A2CSNK2A1MEN1KMT2ATSHR | |
| SCHEMBL9075797 | 0.81 | PDE5A (0.37) | KMT2ATSHRMAPK1MAPTNPC1 | |
| SCHEMBL13609548 | 0.81 | CSNK2A2 (0.40) | CSNK2A2CSNK2A1MEN1KMT2ATSHR | |
| SCHEMBL4255385 | 0.80 | L3MBTL1 (0.54) | CSNK2A2CSNK2A1MEN1KMT2ATSHR | |
| SCHEMBL27712731 | 0.80 | CSNK2A2 (0.39) | CSNK2A2CSNK2A1MEN1KMT2ATSHR | |
| SCHEMBL4255127 | 0.79 | NPC1 (0.42) | CSNK2A2CSNK2A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-12 | — | — | US | disclosed |
| EP-1921074-A1 | THIAZOLE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281142-A1 | THIAZOLE DERIVATIVE | GK, GCKR, AK2 | CSNK2A2 1200/4885CSNK2A1 1582/4885MEN1 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.