⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259544 | 0.82 | — | — | |
| SCHEMBL19173 | 0.67 | — | — | |
| SCHEMBL10630088 | 0.66 | NPC1 (0.41) | — | |
| SCHEMBL6206473 | 0.65 | TGFBR1 (0.37) | — | |
| SCHEMBL21245780 | 0.65 | DYRK1A (0.42) | — | |
| SCHEMBL12920475 | 0.65 | — | — | |
| SCHEMBL31338725 | 0.65 | PDE10A (0.45) | — | |
| SCHEMBL31674379 | 0.65 | PDE10A (0.45) | — | |
| Hydrochloric Acid SCHEMBL6894527 | 0.65 | PDE10A (0.45) | — | |
| Pyridine SCHEMBL28190620 | 0.64 | DYRK1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 680 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250258182-A1 | ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT | IDEXX LABORATORIES, INC. (US) | 2025-08-14 | — | — | US | claimed |
| CN-118164990-A | Method for synthesizing pyrazolo [1,5-a ] [1,3,5] triazine derivative intermediate by boron trifluoride catalysis under microwave radiation | 陕西师范大学 | 2024-06-11 | — | — | CN | claimed |
| CN-114181217-B | Pyrazolo [1,5-a ] [1,3,5] triazine derivative and salt thereof and application of derivative and salt thereof in preparation of anti-cancer drugs | 陕西师范大学 | 2022-12-27 | — | — | CN | claimed |
| CN-110950871-B | 2-substituted-4-arylamino pyrazolotriazine derivative and application thereof in preparing antitumor drugs | 陕西师范大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114181217-A | Pyrazolo [1,5-a ] [1,3,5] triazine derivative and salt thereof and application of derivative and salt thereof in preparation of anti-cancer drugs | 陕西师范大学 | 2022-03-15 | — | — | CN | claimed |
| US-11186576-B2 | Pyrazolo[1,5-A][1,3,5]triazine and pyrazolo[1,5-A]pyrimidine derivatives as CDK inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2021-11-30 | — | — | US | claimed |
| US-20180258092-A9 | Pyrazolo[1,5-A][1,3,5]Triazine and Pyrazolo[1,5-A]Pyrimidine Derivatives as CDK Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-09-13 | — | — | US | claimed |
| US-20180057497-A1 | Pyrazolo[1,5-A][1,3,5]Triazine and Pyrazolo[1,5-A]Pyrimidine Derivatives as CDK Inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-01 | — | — | US | claimed |
| US-20030170731-A1 | Diagnosis and treatment of non-ulcer dyspepsia based on hypothalamic-pituitary-adrenal axis abnormallity | MALOPE COMPANY LIMITED (IE) | 2003-09-11 | — | — | US | claimed |
| EP-1305637-A2 | DIAGNOSIS AND TREATMENT OF NON-ULCER DYSPEPSIA BASED ON HYPOTHALAMIC-PITUITARY-ADRENAL AXIS ABNORMALITY | Malope Company Limited (IE) | 2003-05-02 | — | — | EP | claimed |
| WO-2002010756-A2 | DIAGNOSIS AND TREATMENT OF NON-ULCER DYSPEPSIA BASED ON HYPOTHALAMIC-PITUITARY-ADRENAL AXIS ABNORMALITY | MALOPE COMPANY LIMITED (IE) | 2002-02-07 | — | — | WO | claimed |
| US-12606561-B2 | Substituted pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | QURIENT CO., LTD. (KR) | 2026-04-21 | — | — | US | disclosed |
| US-12606561-B2 | Substituted pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | QURIENT CO., LTD. (KR) | 2026-04-21 | — | — | US | disclosed |
| US-20260041693-A1 | COMBINATION THERAPY OF CDK7 INHIBITORS WITH OTHER ANTI-CANCER THERAPIES | QURIENT CO LTD (KR) | 2026-02-12 | — | — | US | disclosed |
| EP-4192833-B1 | PHARMACOLOGICALLY ACTIVE HETEROCYCLIC-SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2026-01-21 | — | — | EP | disclosed |
| EP-0172608-B1 | NOVEL TRIAZINE DERIVATIVE, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | BIOMEASURE, INC. (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4734414-A | Anti-inflammatory and anti-arthritic pyrazolo-[1,5-a]-1,3,5-triazine derivatives, compositions, and method of use therefor | BIOMEASURE, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4565815-A | Pyrazolo[1,5-a]-1,3,5-triazines | BIOMEASURE, INC. (US) | 1986-01-21 | — | — | US | disclosed |
| US-3910907-A | Pyrazolo(1,5-a)-1,3,5-triazines | VIRATEK, INC., A CORP. OF DE. | 1975-10-07 | — | — | US | disclosed |
| US-3910907-A | Pyrazolo(1,5-a)-1,3,5-triazines | VIRATEK, INC., A CORP. OF DE. | 1975-10-07 | — | — | US | disclosed |