Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21245780 | 0.75 | DYRK1A (0.42) | TGFBR1DYRK1ASCN5AGRM4 | |
| SCHEMBL19896543 | 0.75 | NAMPT (0.33) | TGFBR1DYRK1AHTT | |
| SCHEMBL30013744 | 0.75 | TGFBR1 (0.35) | TGFBR1DYRK1AALDH1A1HSD17B10KDM4E | |
| SCHEMBL26516074 | 0.71 | TGFBR1 (0.50) | TGFBR1DYRK1AALDH1A1KDM4EMAPT | |
| SCHEMBL30363789 | 0.71 | TGFBR1 (0.41) | TGFBR1DYRK1AALDH1A1HSD17B10KDM4E | |
| SCHEMBL5441828 | 0.71 | RPS6KA5 (0.35) | DYRK1A | |
| SCHEMBL2750457 | 0.68 | TGFBR1 (0.51) | TGFBR1DYRK1AALDH1A1KDM4EMAPT | |
| SCHEMBL9429556 | 0.67 | RAB9A (0.46) | ALDH1A1HSD17B10KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29941434 | 0.67 | JAK2 (0.53) | DYRK1AKDM4EMAPT | |
| SCHEMBL12094183 | 0.67 | DYRK1A (0.39) | DYRK1AALDH1A1HSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592691-A1 | PYRAZOLO[1,5-A][1,3,5]TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069837-A1 | PYRAZOLO`1,5-A!`1,3,5!TRIAZINE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2004-08-19 | — | — | WO | disclosed |