Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353523 | 1.00 | L3MBTL1 (0.38) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL16572513 | 0.93 | FGFR2 (0.35) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL6559525 | 0.87 | L3MBTL1 (0.35) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL28472673 | 0.87 | KDM4E (0.39) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL29562631 | 0.85 | CYP1A2 (0.40) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL429654 | 0.85 | CYP1A2 (0.40) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL2880932 | 0.85 | TSHR (0.36) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL1064785 | 0.85 | L3MBTL1 (0.43) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL8746461 | 0.84 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL29545875 | 0.84 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230552-B | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-110635045-B | Water/alcohol soluble organic solar cell anode modification layer material and preparation method thereof | 南昌航空大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114230552-A | Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate | 江苏广域化学有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-110635045-A | Water/alcohol soluble organic solar cell anode modification layer material and preparation method thereof | 南昌航空大学 | 2019-12-31 | — | — | CN | claimed |
| CN-114231295-B | Liquid crystal composition containing substituted cyclohexyl compound and application thereof | 重庆汉朗精工科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-114231294-B | Negative liquid crystal composition and application thereof | 重庆汉朗精工科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-114231296-B | Negative liquid crystal composition and application | 重庆汉朗精工科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117510421-B | Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof | 河北美星化工有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117599687-A | Synthesis device of 4-ethoxy-2, 3-difluorophenol | 浙江吉泰新材料股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117510421-A | Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof | 河北美星化工有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117402041-A | Synthesis method of 4-ethoxy-2, 3-difluorophenol | 浙江吉泰新材料股份有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117143071-A | Preparation method of trans-1, 3-dioxane liquid crystal compound | 宁夏中星显示材料有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-7087272-B2 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | MERCK PATENT GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| US-20050104039-A1 | 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-05-19 | — | — | US | disclosed |
| US-20040106798-A1 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-1373434-A1 | FLUORINATED FLUORENE DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002079344-A1 | FLUORINATED FLUORENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-10 | — | — | WO | disclosed |
| US-6420584-B1 | DEPROTONATION USING ALKYL- OR ARYLMETAL COMPOUNDS OR METAL HYDRIDES IN THE PRESENCE OF A CATALYTIC AMOUNT OF A SECONDARY METAL AMIDE. | MERCK PATENT GMBH (DE) | 2002-07-16 | — | — | US | disclosed |
| US-6207835-B1 | DEPROTONATION IN CONTINUOUS FLOW REACTOR | MERCK KGAA (DE) | 2001-03-27 | — | — | US | disclosed |
| US-5262556-A | Alkylation or hydroxyalkylation by deprotonation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050104039-A1 | 4-ethoxy-2,3,3'-trifluoro-4'-(4-pentyl-cyclohex-3-enyl)-biphenyl; high voltage holding ratio, high TNI, rapid respondse speed | CACNA1I, TBRG4, CACNA1E | L3MBTL1 1786/4885CYP1A2 2550/4885CYP2D6 3635/4885 |
| US-20040106798-A1 | negative anisotropy of the dielectric constants; liquid-crystalline media and optical and electro-optical display elements | H1-0, F3, H1-2 | L3MBTL1 478/4885CYP1A2 3731/4885CYP2D6 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.