SCHEMBL4256173

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4257264	0.92	KDR (0.67)	KDRALDH1A1KDM4EGAACYP1A2
	SCHEMBL4262627	0.91	KDR (0.65)	KDRALDH1A1KDM4EGAACYP1A2
	SCHEMBL14396885	0.91	KDR (0.65)	KDRALDH1A1KDM4EGAACYP1A2
	SCHEMBL13855584	0.90	KDR (0.64)	KDRALDH1A1KDM4EGAACYP1A2
	SCHEMBL4253262	0.89	KDR (0.60)	KDRALDH1A1KDM4EGAACYP1A2
	SCHEMBL4262631	0.89	KDR (0.82)	KDRRAF1PLK4AURKAMAPK13
	SCHEMBL4258987	0.88	KDR (0.61)	KDRRAF1MAPTPLK4AURKA
	SCHEMBL4258983	0.88	KDR (0.79)	KDRRAF1PLK4AURKAMAPK13
	SCHEMBL4253679	0.88	KDR (1.00)	KDRRAF1PLK4AURKAMAPK13
	SCHEMBL4255250	0.88	KDR (0.78)	KDRALDH1A1RAF1PLK4AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.