SCHEMBL4255250

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4256704	0.93	KDR (0.68)	KDRALDH1A1RAF1MAPK14AURKA
	SCHEMBL14396884	0.92	KDR (0.66)	KDRALDH1A1RAF1MAPK14TNNI3K
	SCHEMBL4258983	0.91	KDR (0.79)	KDRRAF1MAPK14TNNI3KPLK4
	SCHEMBL4253263	0.88	ALDH1A1 (0.59)	KDRALDH1A1RAF1MAPK14TNNI3K
	SCHEMBL4256173	0.88	KDR (0.78)	KDRALDH1A1RAF1MAPK14TNNI3K
	SCHEMBL4253679	0.88	KDR (1.00)	KDRRAF1MAPK14TNNI3KPLK4
	SCHEMBL4262631	0.87	KDR (0.82)	KDRRAF1MAPK14TNNI3KPLK4
	SCHEMBL4258982	0.86	KDR (0.76)	KDRALDH1A1RAF1MAPK14TNNI3K
	SCHEMBL14397094	0.85	KDR (0.57)	KDRALDH1A1RAF1MAPK14TNNI3K
	SCHEMBL2335476	0.85	RAF1 (0.72)	KDRALDH1A1RAF1MAPK14TNNI3K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.