Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL4256245 | 1.00 | RAB9A (0.32) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5393178 | 0.92 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL22340623 | 0.92 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL5393184 | 0.92 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL22322845 | 0.82 | CYP2C9 (0.33) | RAB9A | |
| SCHEMBL4256247 | 0.75 | CYP2C9 (0.30) | — | |
| Perchlorate SCHEMBL10416525 | 0.73 | — | — | |
| Perchlorate SCHEMBL10494950 | 0.69 | — | — | |
| Perchlorate SCHEMBL10494955 | 0.69 | — | — | |
| Perchlorate SCHEMBL11496469 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-B1 | 3-Heterocyclyl-Azetidine compounds useful as NK1/NK2 receptors antagonists | ALBIREO AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| US-7402581-B2 | Azetidine compounds | ALBIREO AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-20060172988-A1 | Azetidine compounds | ALBIREO AB (SE) | 2006-08-03 | — | — | US | disclosed |
| US-3966791-A | Preparation of dialkyl amino acrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3965141-A | Process for producing dialkyl aminoacrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172988-A1 | Azetidine compounds | HRH2, HRH4, HRH1 | RAB9A 306/4885KMT2A 2681/4885SMN1; SMN2 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.