Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110064 | 0.81 | POLB (0.54) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL14919416 | 0.78 | POLB (0.51) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL28668767 | 0.75 | POLB (0.52) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL3971910 | 0.74 | POLB (0.51) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL20787377 | 0.73 | NPSR1 (0.47) | POLBL3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL16503885 | 0.73 | POLB (0.47) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL28929688 | 0.71 | MAPT (0.56) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL28670431 | 0.70 | CFTR (0.50) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL28677624 | 0.70 | UTS2R (0.57) | POLBL3MBTL1LMNATP53MAPT | |
| SCHEMBL12836261 | 0.69 | ADRA1D (0.58) | POLBL3MBTL1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009052191-A1 | INTERNALLY MASKED NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. (US) | 2009-04-23 | — | — | WO | disclosed |