Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 5/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002415 | 0.86 | AVPR1A (0.42) | PROKR1AVPR1APKMHTR1AGFER | |
| SCHEMBL27888816 | 0.83 | AVPR1A (0.39) | PROKR1AVPR1ASPRALDH1A1HPGD | |
| SCHEMBL6218887 | 0.81 | AVPR1A (0.51) | PROKR1AVPR1ATACR3PKMENPP2 | |
| SCHEMBL2001801 | 0.76 | POLB (0.42) | — | |
| SCHEMBL6002433 | 0.75 | AVPR1A (0.42) | PROKR1AVPR1APKMHTR1AALDH1A1 | |
| SCHEMBL17436091 | 0.71 | PDE4B (0.47) | PKMGRM5ALDH1A1HPGDHSD17B10 | |
| SCHEMBL939096 | 0.71 | PROKR1 (0.63) | PROKR1GFERALDH1A1HPGD | |
| SCHEMBL937205 | 0.71 | PROKR1 (0.63) | PROKR1PKMGFERALDH1A1HPGD | |
| SCHEMBL22904160 | 0.71 | PROKR1 (0.46) | PROKR1ENPP2ATXN2ALDH1A1CYP3A4 | |
| SCHEMBL7492026 | 0.70 | SIGMAR1 (0.54) | PROKR1GFERHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694677-B1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |