Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256792 | 0.86 | PROKR1 (0.43) | AVPR1APROKR1CYP3A4GFERALDH1A1 | |
| SCHEMBL6002433 | 0.82 | AVPR1A (0.42) | AVPR1APROKR1CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL6218887 | 0.80 | AVPR1A (0.51) | AVPR1APROKR1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL12566957 | 0.73 | POLB (0.49) | TSHR | |
| SCHEMBL937205 | 0.72 | PROKR1 (0.63) | PROKR1SMN1; SMN2GFERKDM4EALDH1A1 | |
| SCHEMBL939096 | 0.72 | PROKR1 (0.63) | PROKR1GFERKDM4EALDH1A1HPGD | |
| SCHEMBL22904160 | 0.72 | PROKR1 (0.46) | PROKR1CYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL24996458 | 0.72 | OTUD7B (0.37) | CYP1A2SMN1; SMN2 | |
| SCHEMBL30763484 | 0.72 | OTUD7B (0.37) | CYP1A2SMN1; SMN2 | |
| SCHEMBL7492026 | 0.71 | SIGMAR1 (0.54) | PROKR1GFERKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |