Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406308 | 1.00 | DPP4 (0.44) | DPP4DPP8DPP7DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL2744138 | 0.89 | DPP8 (0.41) | DPP4DPP8DPP7DPP9ABHD6 | |
| SCHEMBL8060885 | 0.85 | XIAP (0.36) | DPP4DPP8DPP7DPP9ABHD6 | |
| SCHEMBL8239266 | 0.84 | DPP8 (0.39) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8187686 | 0.84 | DPP8 (0.35) | DPP8DPP7DPP9KCNH2ABHD6 | |
| SCHEMBL4259244 | 0.82 | ELANE (0.37) | — | |
| SCHEMBL14963381 | 0.80 | DDB1 (0.42) | DPP8DPP7DPP9ABHD6 | |
| SCHEMBL4655478 | 0.80 | DDB1 (0.42) | DPP8DPP7DPP9ABHD6 | |
| SCHEMBL6913773 | 0.80 | DDB1 (0.42) | DPP8DPP7DPP9ABHD6 | |
| SCHEMBL2805310 | 0.80 | DDB1 (0.42) | DPP8DPP7DPP9ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |