Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254592 | 0.89 | PARP15 (0.38) | PARP15TNKS2PARP2 | |
| SCHEMBL4263334 | 0.89 | — | — | |
| SCHEMBL2932070 | 0.87 | — | — | |
| SCHEMBL2932072 | 0.87 | — | — | |
| SCHEMBL4257117 | 0.86 | MAPT (0.46) | PARP15TNKS2PARP2 | |
| SCHEMBL4267680 | 0.86 | MAPT (0.46) | PARP15TNKS2PARP2 | |
| SCHEMBL4267705 | 0.83 | — | — | |
| SCHEMBL4267686 | 0.81 | PARP15 (0.41) | PARP15TNKS2PARP2 | |
| SCHEMBL4259817 | 0.78 | PARP15 (0.38) | PARP15TNKS2PARP2 | |
| SCHEMBL4263337 | 0.76 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499622-B1 | HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS | WYETH CORP (US) | 2009-03-11 | — | — | EP | claimed |