Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267680 | 0.93 | MAPT (0.46) | PARP15PARP10TNKS2PARP2LMNA | |
| SCHEMBL4257117 | 0.93 | MAPT (0.46) | PARP15PARP10TNKS2PARP2LMNA | |
| SCHEMBL4267705 | 0.86 | — | — | |
| SCHEMBL2932072 | 0.84 | — | — | |
| SCHEMBL2932070 | 0.84 | — | — | |
| SCHEMBL4254592 | 0.83 | PARP15 (0.38) | PARP15PARP10TNKS2PARP2MAPT | |
| SCHEMBL4257282 | 0.81 | PARP15 (0.38) | PARP15TNKS2PARP2 | |
| SCHEMBL4257122 | 0.81 | TP53 (0.44) | PARP15PARP10TNKS2PARP2LMNA | |
| SCHEMBL4259771 | 0.78 | BRPF1 (0.38) | — | |
| SCHEMBL4259814 | 0.78 | BRPF1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499622-B1 | HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS | WYETH CORP (US) | 2009-03-11 | — | — | EP | claimed |