Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262075 | 0.90 | PARP15 (0.36) | MAPTTP53THRB | |
| SCHEMBL4267704 | 0.86 | — | — | |
| SCHEMBL4263334 | 0.86 | — | — | |
| SCHEMBL4267705 | 0.79 | — | — | |
| SCHEMBL4259772 | 0.79 | BRPF1 (0.36) | — | |
| SCHEMBL4257558 | 0.76 | — | — | |
| SCHEMBL4257282 | 0.76 | PARP15 (0.38) | — | |
| SCHEMBL4254592 | 0.76 | PARP15 (0.38) | MAPT | |
| SCHEMBL4261702 | 0.76 | NPC1 (0.37) | MAPTTP53 | |
| SCHEMBL4259319 | 0.76 | NPC1 (0.35) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499622-B1 | HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS | WYETH CORP (US) | 2009-03-11 | — | — | EP | claimed |