Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329366 | 0.79 | TDP1 (0.44) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL6480647 | 0.70 | TDP1 (0.45) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL30587859 | 0.70 | ALDH1A1 (0.34) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL29826970 | 0.70 | TDP1 (0.45) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1673437 | 0.69 | HTR2A (0.39) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| Methane SCHEMBL27917831 | 0.68 | TDP1 (0.43) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL27798784 | 0.68 | TDP1 (0.43) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL5141868 | 0.68 | HTR2A (0.36) | — | |
| SCHEMBL7199928 | 0.68 | KDM4E (0.38) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL845626 | 0.67 | CYP2D6 (0.56) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057245-A2 | PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008027515-A2 | PHOSPHORUS-CONTAINING STABILIZERS FOR FLUOROOLEFINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-03-06 | — | — | WO | disclosed |