SCHEMBL6480647

SCHEMBL6480647

c1ccc(CC2CO2)c(CC2CO2)c1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 3/20 0.41
GLA P06280 1/20 0.41
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
CTSB P07858 1/20 0.38
DHFR P00374 1/20 0.38
CHRM2 P08172 4/20 0.36
CHRM4 P08173 4/20 0.36
CHRM1 P11229 4/20 0.36
CHRM3 P20309 4/20 0.36
CHRM5 P08912 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29826970 1.00 TDP1 (0.45) TDP1ALDH1A1GLATSHRTP53
SCHEMBL28454337 0.93 TDP1 (0.41) TDP1ALDH1A1GLATSHRTP53
SCHEMBL30607492 0.93 TDP1 (0.41) TDP1ALDH1A1GLATSHRTP53
SCHEMBL28370227 0.89 IDO1 (0.40) TDP1ALDH1A1GLATSHRTP53
SCHEMBL2675606 0.88 TDP1 (0.41) TDP1ALDH1A1GLATSHRTP53
SCHEMBL29169840 0.87 TDP1 (0.37) TDP1ALDH1A1GLATSHRTP53
SCHEMBL8660205 0.87 TDP1 (0.50) TDP1ALDH1A1GLATSHRTP53
SCHEMBL9501375 0.87 CYP2D6 (0.42) TDP1ALDH1A1GLATSHRTP53
SCHEMBL4464583 0.87 TDP1 (0.41) TDP1ALDH1A1GLATSHRTP53
SCHEMBL31438264 0.86 ALDH1A1 (0.48) TDP1ALDH1A1GLATSHRCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106715528-B The eugenol polyethers of hydrosilylation and the preparation of eugenol polyether silicone and application thereof 赢创德固赛有限公司 2019-08-23 CN claimed
CN-109890861-A Thermoset composition and three-dimension object is formed by it 帝斯曼知识产权资产管理有限公司 2019-06-14 CN claimed
CN-108482755-A A kind of foods package closing machine 徐州工程学院 2018-09-04 CN claimed
CN-107250062-A Scale inhibitor composition and application method 塞特工业公司 2017-10-13 CN claimed
CN-107207721-A Modified alkoxylated product with least one non-end alkoxysilyl, the storage stability with raising and improved elongation and the polymer using their preparations 赢创德固赛有限公司 2017-09-26 CN claimed
CN-107098798-A The modifying agent for including benzylalcohol alcoxylates for curable compositions 赢创德固赛有限公司 2017-08-29 CN claimed
CN-109642009-B Silane-functional polymeric polyurethanes 科思创德国股份有限公司 2021-12-10 CN disclosed
CN-110290853-A For carrying out the stable immobilization amine sorbent of REE and heavy metal recovery from fluid supply PQ公司 2019-09-27 CN disclosed
CN-105835478-B Surface treatment copper foil and product about it JX 金属株式会社 2019-08-09 CN disclosed
CN-109982829-A Thermoset composition and three-dimension object is formed by it 帝斯曼知识产权资产管理有限公司 2019-07-05 CN disclosed
CN-109896955-A A kind of preparation method of beta-hydroxycarboxylic acids ester 沈阳金久奇科技有限公司 2019-06-18 CN disclosed
CN-109890861-A Thermoset composition and three-dimension object is formed by it 帝斯曼知识产权资产管理有限公司 2019-06-14 CN disclosed
CN-106544063-B The succinimide that hydroxyalkyl replaces and the fuel containing it 雅富顿化学公司 2019-05-03 CN disclosed
US-5182344-A Transesterification; free of secondary hydroxyl groups; thermoforming; melt-processible; latently thermosetting THE DOW CHEMICAL COMPANY (US) 1993-01-26 US disclosed
EP-0489417-A2 A cross-linked semi-permeable gas separation membrane substantially derived from a reaction product of a thermoformable, thermosettable aromatic polycarbonate, polyestercarbonate, and/or polyester polymer and an epoxy resin THE DOW CHEMICAL COMPANY (US) 1992-06-10 EP disclosed
US-5037903-A A thermoformable, thermosetting blend of hydrogen-free epoxides and hydrogen-free polyesters or polycarbonates or copolymers and a polyorganophosphonium salt catalyst THE DOW CHEMICAL COMPANY (US) 1991-08-06 US disclosed
EP-0417601-A2 Thermoformable, thermosettable epoxy/polyester reaction products THE DOW CHEMICAL COMPANY (US) 1991-03-20 EP disclosed
US-4783519-A High functionality, low melt viscosity, flakable solid epoxy resin with good heat resistance THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed
US-4764580-A High functionality, low melt viscosity, flakable solid epoxy resin with good heat resistance THE DOW CHEMICAL COMPANY (US) 1988-08-16 US disclosed
US-4753999-A ADDITION POLYMER CONTAINING QUATERNARY AMMONIUM MONOMER, IMPROVES COLORFASTNESS OF DYES ON TEXTILES CASSELLA AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed