Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442962 | 0.90 | HDAC3 (0.51) | PIN1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL4252933 | 0.89 | TAS1R3 (0.48) | RAB9ATAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL4255500 | 0.84 | HDAC1 (0.47) | PIN1RAB9ATAS1R3TAS1R1HDAC3 | |
| SCHEMBL4251053 | 0.84 | TAS1R3 (0.62) | NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL4257549 | 0.82 | PIN1 (0.43) | PIN1NPC1RAB9ATAS1R3TAS1R1 | |
| SCHEMBL4256642 | 0.80 | HDAC6 (0.46) | PIN1TAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL4253214 | 0.80 | CNR2 (0.49) | NPC1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL4248075 | 0.80 | MEN1 (0.48) | NPC1RAB9AHDAC1 | |
| SCHEMBL443731 | 0.79 | TAS1R3 (0.52) | RAB9ATAS1R3TAS1R1HDAC3HDAC1 | |
| SCHEMBL4253907 | 0.78 | HDAC8 (0.47) | NPC1RAB9AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC8, HDAC3 | PIN1 3310/4885NPC1 1960/4885RAB9A 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.