Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22513723 | 0.85 | TDP1 (0.41) | TDP1FAAHCES1CES2MEN1 | |
| SCHEMBL10309787 | 0.83 | FAAH (0.40) | TDP1FAAHCES1CES2MEN1 | |
| SCHEMBL3589092 | 0.83 | HTT (0.31) | — | |
| SCHEMBL2487231 | 0.82 | TDP1 (0.31) | TDP1 | |
| SCHEMBL25309973 | 0.82 | CES1 (0.39) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL21078338 | 0.82 | TDP1 (0.43) | TDP1FAAHCES1CES2MEN1 | |
| SCHEMBL6267013 | 0.81 | FAAH (0.42) | TDP1FAAHCES1CES2MEN1 | |
| SCHEMBL16728497 | 0.79 | TDP1 (0.45) | TDP1FAAHMEN1CYP1A2KMT2A | |
| SCHEMBL10584705 | 0.78 | FAAH (0.45) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL31016294 | 0.78 | TDP1 (0.50) | TDP1CES1CES2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110176630-B | Electrolyte solution and electrochemical device using the same | 宁德新能源科技有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-103547552-B | Non-flammable compositions of chloro-trifluoropropene | 阿科玛股份有限公司 | 2017-02-08 | — | — | CN | claimed |
| CN-105917187-A | Method and device for charging stratified thermal energy store | 西门子公司 | 2016-08-31 | — | — | CN | claimed |
| WO-2016010634-A1 | USE OF 1,1,2,2-TETRAFLUOROETHANE IN HIGH TEMPERATURE HEAT PUMPS | THE CHEMOURS COMPANY FC, LLC (US) | 2016-01-21 | — | — | WO | claimed |
| CN-104531078-A | Compositions and methods for reducing fire hazard of flammable refrigerants | DU PONT | 2015-04-22 | — | — | CN | claimed |
| CN-1878849-B | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT | 2014-12-24 | — | — | CN | claimed |
| EP-2791668-A1 | METHOD FOR OPERATING AN ELECTRICAL APPARATUS | ABB Technology AG (CH) | 2014-10-22 | — | — | EP | claimed |
| CN-101687738-B | Use of r-1233 in liquid chillers | ARKEMA INC | 2014-06-11 | — | — | CN | claimed |
| CN-103702658-A | Hair dye composition and method for coloring hair using the same | REVLON CONSUMER PRODUCTS | 2014-04-02 | — | — | CN | claimed |
| EP-2652752-A1 | DIELECTRIC INSULATION MEDIUM | ABB Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| EP-2652753-A1 | DIELECTRIC INSULATION MEDIUM | ABB Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| EP-2652751-A1 | DIELECTRIC INSULATION MEDIUM | ABB Research Ltd. (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130207021-A1 | COMPOSITION OF ZEOTROPIC MIXTURES HAVING PREDEFINED TEMPERATURE GLIDE | RTX CORPORATION | 2013-08-15 | — | — | US | claimed |
| WO-2013087683-A1 | METHOD FOR OPERATING AN ELECTRICAL APPARATUS | ABB TECHNOLOGY AG (CH) | 2013-06-20 | — | — | WO | claimed |
| WO-2012080246-A1 | DIELECTRIC INSULATION MEDIUM | ABB TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080222-A1 | DIELECTRIC INSULATION MEDIUM | ABB RESEARCH LTD (CH) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080269-A1 | DIELECTRIC INSULATION MEDIUM | ABB TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| CN-101687738-A | Use of r-1233 in liquid chillers | ARKEMA INC | 2010-03-31 | — | — | CN | claimed |
| WO-2007100886-A2 | AZEOTROPIC COMPOSITIONS COMPRISING FLUORINATED COMPOUNDS FOR CLEANING APPLICATIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-07 | — | — | WO | claimed |
| EP-4262788-B1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| US-20240101555-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-03-28 | — | — | US | disclosed |
| EP-4262788-A1 | UREA OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2023130043-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS AND USE THEREOF FOR THE TREATMENT OF ANXIETY | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |
| CN-115428245-A | Battery pack having fire extinguishing film containing fire extinguishing microcapsules | GFI有限公司 | 2022-12-02 | — | — | CN | disclosed |
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | C4 THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |
| US-11292853-B2 | Methods and compositions for curing a surface of an uncured polysulfide rubber | THE BOEING COMPANY (US) | 2022-04-05 | — | — | US | disclosed |
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-09-23 | — | — | US | disclosed |
| CN-110176630-B | Electrolyte solution and electrochemical device using the same | 宁德新能源科技有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-20200331870-A1 | MCL-1 INHIBITORS | GILEAD SCIENCES, INC. | 2020-10-22 | — | — | US | disclosed |
| US-20200190226-A1 | METHODS AND COMPOSITIONS FOR CURING A SURFACE OF AN UNCURED POLYSULFIDE RUBBER | THE BOEING COMPANY | 2020-06-18 | — | — | US | disclosed |
| US-10597468-B2 | Methods and compositions for curing a surface of an uncured polysulfide rubber | THE BOEING COMPANY (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190233441-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2019-08-01 | — | — | US | disclosed |
| US-20190023814-A1 | METHODS AND COMPOSITIONS FOR CURING A SURFACE OF AN UNCURED POLYSULFIDE RUBBER | THE BOEING COMPANY | 2019-01-24 | — | — | US | disclosed |
| CN-105026854-B | Use the adsorption system of metal-organic framework | 阿科玛股份有限公司 | 2018-10-02 | — | — | CN | disclosed |
| CN-107126660-A | A kind of composition for including fluorinated ketones contained | 中化蓝天集团有限公司 | 2017-09-05 | — | — | CN | disclosed |
| US-9725402-B2 | Nitroso compounds as nitroxyl donors and methods of use thereof | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| EP-3146531-A1 | ELECTRICAL APPARATUS FOR THE GENERATION, TRANSMISSION, DISTRIBUTION AND/OR USAGE OF ELECTRICAL ENERGY AND METHOD FOR RECOVERING A SUBSTANCE FROM AN INSULATION MEDIUM OF SUCH AN APPARATUS | ABB Schweiz AG (CH) | 2017-03-29 | — | — | EP | disclosed |
| EP-3055867-A1 | APPARATUS FOR THE GENERATION, THE DISTRIBUTION AND/OR THE USAGE OF ELECTRICAL ENERGY AND COMPONENT FOR SUCH AN APPARATUS | ABB Technology AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| US-20160185780-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-06-30 | — | — | US | disclosed |
| CN-105637059-A | Use of alkyl perfluoroalkene ethers and mixtures thereof in high temperature heat pumps | CHEMOURS CO FC LLC | 2016-06-01 | — | — | CN | disclosed |
| CN-103391726-B | The layer structure of adaptability thermal insulation is provided | W.L. GORE & ASSOCIATES GMBH (DE) | 2016-03-16 | — | — | CN | disclosed |
| CN-102696081-B | Comprise the transformer of heat pipe | ABB RESEARCH LTD. (CH) | 2016-02-24 | — | — | CN | disclosed |
| CN-103338667-B | Layered structure providing adaptive thermal insulation | W.L. GORE & ASSOCIATES GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| CN-102460604-B | DIELECTRIC INSULATION MEDIUM | ABB TECHNOLOGY LTD. (CH) | 2015-11-25 | — | — | CN | disclosed |
| CN-105006273-A | Encapsulated switchgear | ABB TECHNOLOGY AG | 2015-10-28 | — | — | CN | disclosed |
| CN-103071260-B | N 2/ CO 2fire extinguishing system propelling gas mixture | KIDDE TECH INC. (US) | 2015-08-19 | — | — | CN | disclosed |
| EP-2904616-A1 | ELECTRICAL INSULATOR COMPRISING AN ORGANOFLUORINE COMPOUND AND METHOD FOR PRODUCING IT | ABB Technology AG (CH) | 2015-08-12 | — | — | EP | disclosed |
| US-20150221987-A1 | ELECTROLYTIC SOLUTION FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY | FUJIFILM CORPORATION (JP) | 2015-08-06 | — | — | US | disclosed |
| CN-103071259-B | Automatic fire extinguishing system having outlet dimensions sized relative to propellant gas pressure | KIDDE TECH INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104788708-A | Compositions comprising 2,3,3,3-tetrafluoropropene and hydrocarbons and uses thereof | DU PONT | 2015-07-22 | — | — | CN | disclosed |
| CN-102460605-B | Encapsulated switching device, method for providing same and use of a dielectric compound having a boiling point above-25 ℃ in its insulating medium | ABB TECHNOLOGY AG | 2015-07-15 | — | — | CN | disclosed |
| US-9039923-B2 | Composition of zeotropic mixtures having predefined temperature glide | UNITED TECHNOLOGIES CORPORATION (US) | 2015-05-26 | — | — | US | disclosed |
| CN-102311099-B | Oxidation treatment method and oxidation treatment apparatus | TAIYO NIPPON SANSO CORP | 2015-05-20 | — | — | CN | disclosed |
| CN-102216411-B | Compositions comprising 2, 3, 3, 3-tetrafluoropropene and hydrocarbons and uses thereof | DU PONT | 2015-04-29 | — | — | CN | disclosed |
| CN-104531078-A | Compositions and methods for reducing fire hazard of flammable refrigerants | DU PONT | 2015-04-22 | — | — | CN | disclosed |
| EP-2814898-A1 | COMPOSITION OF ZEOTROPIC MIXTURES HAVING PREDEFINED TEMPERATURE GLIDE | United Technologies Corporation (US) | 2014-12-24 | — | — | EP | disclosed |
| CN-1878849-B | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT | 2014-12-24 | — | — | CN | disclosed |
| CN-103764737-A | Compositions comprising 1,1,1,2,2-pentafluoropropane and a fluoroolefin and uses thereof | DU PONT | 2014-04-30 | — | — | CN | disclosed |
| WO-2014053462-A1 | ELECTRICAL INSULATOR COMPRISING AN ORGANOFLUORINE COMPOUND AND METHOD FOR PRODUCING IT | ABB TECHNOLOGY AG (CH) | 2014-04-10 | — | — | WO | disclosed |
| CN-103702658-A | Hair dye composition and method for coloring hair using the same | REVLON CONSUMER PRODUCTS | 2014-04-02 | — | — | CN | disclosed |
| CN-101605881-B | Nonflammable compositions comprising fluorinated compounds and use of these compositions | SOLVAY FLUOR GMBH | 2014-03-05 | — | — | CN | disclosed |
| CN-103391726-A | Laminar structure providing adaptive thermal insulation | GORE W L & ASS GMBH | 2013-11-13 | — | — | CN | disclosed |
| CN-103351849-A | Stable formulated systems with chloro-3,3,3-trifluoropropene | ARKEMA INC | 2013-10-16 | — | — | CN | disclosed |
| WO-2013123116-A1 | COMPOSITION OF ZEOTROPIC MIXTURES HAVING PREDEFINED TEMPERATURE GLIDE | UNITED TECHNOLOGIES CORPORATION (US) | 2013-08-22 | — | — | WO | disclosed |
| US-20130207021-A1 | COMPOSITION OF ZEOTROPIC MIXTURES HAVING PREDEFINED TEMPERATURE GLIDE | RTX CORPORATION | 2013-08-15 | — | — | US | disclosed |
| CN-102947410-A | Heat transfer compositions having hydrofluorocarbons and a hydrofluoroolefin | ARKEMA INC | 2013-02-27 | — | — | CN | disclosed |
| US-20120280189-A1 | PERFLUOROKETONES AS GASEOUS DIELECTRICS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-11-08 | — | — | US | disclosed |
| CN-101687738-A | Use of r-1233 in liquid chillers | ARKEMA INC | 2010-03-31 | — | — | CN | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090056349-A1 | COMPOSITIONS COMPRISING 3,3,4,4,5,5,6,6,6-NONAFLUORO-1-HEXENE | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-05 | — | — | US | disclosed |
| EP-2024431-A2 | BLOWING AGENT COMPOSITION | Arkema France (FR) | 2009-02-18 | — | — | EP | disclosed |
| EP-2010596-A2 | BLOWING AGENT COMPOSITION | Arkema France (FR) | 2009-01-07 | — | — | EP | disclosed |
| CN-101184821-A | Compositions comprising 3,3,4,4,5,5,6,6,6-nonafluoro-1-hexene | DU PONT (US) | 2008-05-21 | — | — | CN | disclosed |
| WO-2007113434-A2 | BLOWING AGENT COMPOSITION | ARKEMA FRANCE (FR) | 2007-10-11 | — | — | WO | disclosed |
| WO-2007113435-A2 | BLOWING AGENT COMPOSITION | ARKEMA FRANCE (FR) | 2007-10-11 | — | — | WO | disclosed |
| CN-1878849-A | Composition and method for reducing the fire hazard of flammable refrigerants | DU PONT (US) | 2006-12-13 | — | — | CN | disclosed |
| US-20060266975-A1 | Compositions comprising 3,3,4,4,5,5,6,6,6-nonafluoro-1-hexene | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-11-30 | — | — | US | disclosed |
| US-20060266975-A1 | Compositions comprising 3,3,4,4,5,5,6,6,6-nonafluoro-1-hexene | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185780-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | ABL1, JAK2, JAK1 | TDP1 502/4885FAAH 1866/4885CES1 2377/4885 |
| US-20200331870-A1 | MCL-1 INHIBITORS | MCL1, BCL2L1, BCL2 | TDP1 764/4885FAAH 4132/4885CES1 3816/4885 |
| US-20210292300-A1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | TLR9, TLR7, TLR8 | TDP1 644/4885FAAH 3040/4885CES1 4369/4885 |
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | CRBN, IKZF1, IKZF3 | TDP1 1207/4885FAAH 2259/4885CES1 2610/4885 |
| US-20190233441-A1 | TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | ABL1, JAK2, JAK1 | TDP1 502/4885FAAH 1866/4885CES1 2377/4885 |
| US-20240101555-A1 | UREA OREXIN RECEPTOR AGONISTS | HCRTR1, HCRTR2, UTS2R | TDP1 4531/4885FAAH 188/4885CES1 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.