Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309973 | 0.87 | CES1 (0.39) | — | |
| SCHEMBL15346753 | 0.87 | ACE (0.48) | — | |
| SCHEMBL15512429 | 0.85 | PLA2G4A (0.40) | — | |
| SCHEMBL3950064 | 0.84 | HTT (0.33) | HTT | |
| SCHEMBL4257794 | 0.83 | TDP1 (0.45) | — | |
| SCHEMBL8744846 | 0.83 | GABRR1 (0.46) | — | |
| SCHEMBL21022853 | 0.83 | FAAH (0.32) | — | |
| SCHEMBL6338324 | 0.83 | — | — | |
| SCHEMBL10584705 | 0.83 | FAAH (0.45) | — | |
| SCHEMBL25307541 | 0.81 | PLA2G4A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111914-A | A kind of ultraviolet enhanced film of rare earth compounding | 合肥工业大学 | 2019-01-01 | — | — | CN | claimed |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | TOKUYAMA CORPORATION (JP) | 2026-04-07 | — | — | US | disclosed |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-03-27 | — | — | US | disclosed |
| EP-4471018-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2024-12-04 | — | — | EP | disclosed |
| CN-118574819-A | Photochromic compound, naphthol derivative, curable composition, optical article, lens and spectacles | 株式会社德山 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| WO-2022196523-A1 | FLUORINE-CONTAINING COMPOUND AND CONTRAST AGENT | TDK株式会社 | 2022-09-22 | — | — | WO | disclosed |
| CN-109705839-A | A kind of rare-earth europium hybrid mesoporous luminescent material of terpyridyl derivative functionalization and its preparation method and application | 河北科技大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106011485-B | From the method for extracting scandium oxide in waste residue containing scandium | 潮州三环（集团）股份有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-108610483-A | A kind of high-purity dimethicone of resistance to oxidation and its synthetic method | 广州盛泰诺新材料科技有限公司 | 2018-10-02 | — | — | CN | disclosed |
| US-20100190687-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-07-29 | — | — | US | disclosed |
| US-20100048623-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME LLC | 2010-02-25 | — | — | US | disclosed |
| EP-2013171-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER S DISEASE | Merck Sharp & Dohme Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008130581-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2007125364-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER’S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |
| US-6136847-A | Water-soluble trioxanes as potent and safe antimalarial agents | JOHNS HOPKINS UNIVERSITY (US) | 2000-10-24 | — | — | US | disclosed |
| WO-2000059501-A1 | WATER-SOLUBLE TRIOXANES AS POTENT AND SAFE ANTIMALARIAL AGENTS | JOHNS HOPKINS UNIVERSITY (US) | 2000-10-12 | — | — | WO | disclosed |
| US-5932591-A | C3 substituted trioxanes useful as antiparasitic drugs | JOHNS HOPKINS UNIVERSITY (US) | 1999-08-03 | — | — | US | disclosed |
| US-4633023-A | Fluoroacrylate ester, polymer thereof, and process of making the same | GEO-CENTERS, INC. (US) | 1986-12-30 | — | — | US | disclosed |
| US-4578508-A | Fluoroacrylate ester, polymer thereof, and process of making the same | GEO-CENTERS, INC. (US) | 1986-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | CRYAA, CRYZ, CRY2 | HTT 2122/4885NAMPT 3219/4885 |
| US-20100190687-A1 | PYRIMIDINONE DERIVATIVES AND METHODS OF USE THEREOF | GPR119, GCGR, GPR65 | HTT 1931/4885NAMPT 523/4885 |
| US-20250101294-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | NAP1L1, CRYAA, CRYZ | HTT 1900/4885NAMPT 702/4885 |
| US-20100048623-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | BACE1, PSEN1, BACE2 | HTT 552/4885NAMPT 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.