Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.43 |
| ▸ | IDH2 | P48735 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361415 | 0.77 | SLC40A1 (0.52) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL17372076 | 0.77 | L3MBTL1 (0.65) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL18881310 | 0.77 | L3MBTL1 (0.65) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL17491033 | 0.75 | L3MBTL1 (0.49) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL14093070 | 0.74 | KMT2A (0.36) | L3MBTL1IDH2ALDH1A1LMNA | |
| SCHEMBL16792132 | 0.74 | L3MBTL1 (0.56) | L3MBTL1KAT6ASLC40A1GLO1ALDH1A1 | |
| SCHEMBL17489126 | 0.74 | L3MBTL1 (0.59) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL5152771 | 0.73 | L3MBTL1 (0.59) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL10362240 | 0.73 | L3MBTL1 (0.59) | L3MBTL1KAT6ASLC40A1GLO1KDM4E | |
| SCHEMBL10438614 | 0.73 | KAT6A (0.63) | L3MBTL1KAT6ASLC40A1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046782-A2 | IMIDAZOLYLPYRIMIDINE DERIVATIVES FOR TREATMENT OF DISEASES RELATED TO GLYCOGEN SYNTHASE KINASE (GSK3) | Astra Zeneca AB (SE) | 2009-04-15 | — | — | EP | claimed |
| WO-2008002244-A2 | IMIDAZOL-PYRIMIDINE DERIVATIVES FOR TREATMENT OF DISEASES RELATED TO GLYCOGEN SYNTHASE KINASE (GSK3) | ASTRAZENECA AB (SE) | 2008-01-03 | — | — | WO | claimed |