Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 known ✓ | P04062 | 1/20 | 0.34 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9581035 | 1.00 | MEN1 (0.52) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL2223494 | 0.98 | MEN1 (0.55) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL5257688 | 0.98 | MEN1 (0.55) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL29697295 | 0.98 | MEN1 (0.55) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL21246910 | 0.95 | CYP3A4 (0.59) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL27453848 | 0.95 | MEN1 (0.52) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL188002 | 0.90 | LMNA (0.46) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL8167949 | 0.90 | LMNA (0.46) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL2586847 | 0.90 | LMNA (0.46) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Cadaverine Tartrate SCHEMBL9581037 | 0.90 | LMNA (0.46) | MEN1LMNAKMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181437-A1 | Method for producing a conjugated linoleic acid glyceride | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20070196446-A1 | Conjugated fatty acid esters | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20060257454-A1 | Conjugated fatty acid esters | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-11-16 | — | — | US | disclosed |
| US-20050165100-A1 | Conjugated fatty acid esters | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1174416-A1 | CONJUGATED FATTY ACID ESTERS | Kabushiki Kaisha Yakult Honsha (JP) | 2002-01-23 | — | — | EP | disclosed |