SCHEMBL4258146

SCHEMBL4258146

CCC(CC)C(O)C(C)C(C)O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17581985 0.84 TSHR (0.47) TSHRLMNATDP1
SCHEMBL8370213 0.84 TSHR (0.47) TSHRLMNATDP1
SCHEMBL4438548 0.80 ALDH1A1 (0.38) TSHRLMNATDP1
SCHEMBL4885233 0.79 TSHR (0.47) TSHRLMNA
SCHEMBL19758113 0.78 TSHR (0.47) TSHRLMNATDP1
SCHEMBL9121762 0.78 TSHR (0.47) TSHRLMNATDP1
SCHEMBL19758139 0.78 TSHR (0.47) TSHRLMNATDP1
SCHEMBL5931064 0.77 LMNA (0.48) TSHRLMNATDP1
SCHEMBL13062787 0.76
SCHEMBL428149 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220081635-A1 SYNTHETIC ESTERS DERIVED FROM HIGH STABILITY OLEIC ACID QUAKER CHEMICAL CORPORATION (US) 2022-03-17 US claimed
US-11155761-B2 Synthetic esters derived from high stability oleic acid QUAKER CHEMICAL CORPORATION (US) 2021-10-26 US claimed
EP-3298112-B1 SYNTHETIC ESTERS DERIVED FROM HIGH STABILITY OLEIC ACID QUAKER CHEM CORP (US) 2023-05-10 EP disclosed
US-20220081635-A1 SYNTHETIC ESTERS DERIVED FROM HIGH STABILITY OLEIC ACID QUAKER CHEMICAL CORPORATION (US) 2022-03-17 US disclosed
US-11155761-B2 Synthetic esters derived from high stability oleic acid QUAKER CHEMICAL CORPORATION (US) 2021-10-26 US disclosed
US-10851291-B2 Coated particles, methods for their manufacture and for their use as proppants COVESTRO LLC (US) 2020-12-01 US disclosed
US-20200181483-A1 COATED PARTICLES, METHODS FOR THEIR MANUFACTURE AND FOR THEIR USE AS PROPPANTS COVESTRO LLC (US) 2020-06-11 US disclosed
US-10647911-B2 Coated particles, methods for their manufacture and for their use as proppants COVESTRO LLC (US) 2020-05-12 US disclosed
CN-110997863-A Coated particles, methods of making and using the same as proppants 科思创有限公司 2020-04-10 CN disclosed
US-20190330521-A1 COATED PARTICLES, METHODS FOR THEIR MANUFACTURE AND FOR THEIR USE AS PROPPANTS COVESTRO LLC (US) 2019-10-31 US disclosed
US-10385261-B2 Coated particles, methods for their manufacture and for their use as proppants COVESTRO LLC (US) 2019-08-20 US disclosed
US-20090156777-A1 Freeze-stable aromatic diisocyanates and processes for the preparation of these freeze-stable products BAYER MATERIALSCIENCE LLC 2009-06-18 US disclosed
EP-1122270-B1 Process for the preparation of polyisocyanate compositions based on MDI with improved freeze stability BAYER AG (US) 2004-05-06 EP disclosed
EP-1122271-B1 Process for the preparation of polyisocyanate compositions based on MDI with improved freeze stability BAYER AG (US) 2004-03-31 EP disclosed
US-6482913-B1 Liquid MDI adducts wtih improved freeze stability BAYER AKTIENGESELLSCHAFT (DE) 2002-11-19 US disclosed
EP-1122271-A1 Liquid MDI adducts with improved freeze stability Bayer Corporation (US) 2001-08-08 EP disclosed
EP-1122270-A1 Liquid MDI adducts with improved freeze stability Bayer Corporation (US) 2001-08-08 EP disclosed
US-6242556-B1 OF AN ALLOPHONATE-MODIFIED DIPHENYLMETHANE DIISOCYANATE(=MDI)WITH AN ISOCYANATE GROUP CONTENT OF FROM 12 TO 32.5% AND A DIPHENYLMETHANE DIISOCYANATE ADDUCT WITH AN ISOCYANATE GROUP CONTENT OF FROM 15 TO 30& BAYER CORPORATION 2001-06-05 US disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-3956154-A AIRCRAFT STAUFFER CHEMICAL COMPANY (US) 1976-05-11 US disclosed