Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644778 | 1.00 | HTR3A (0.46) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL4258364 | 1.00 | HTR3A (0.46) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL2141187 | 0.96 | HTR3A (0.46) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL1645815 | 0.96 | HTR3A (0.46) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL2141184 | 0.96 | HTR3A (0.46) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| Hydrochloric Acid SCHEMBL7309317 | 0.94 | HTR2A (0.47) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL16451639 | 0.87 | HTR2A (0.47) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15282173 | 0.87 | HTR2A (0.47) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL15291807 | 0.87 | HTR2A (0.47) | HTR3AHTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL17806041 | 0.87 | HTR2A (0.47) | HTR3AHTR2AHTR2CHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833782-B1 | CYCLOALKYLAMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | EP | disclosed |