Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 7/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17806041 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL15282173 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL15291807 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| Hydrochloric Acid SCHEMBL16372230 | 0.98 | HTR2A (0.50) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL2141184 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL2141187 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL1645815 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL4258361 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL4258364 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A | |
| SCHEMBL1644778 | 0.87 | HTR3A (0.46) | HTR2AHTR2CHTR2BHTR3AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867371-B2 | 4-membered ring carboxamides used as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-9414589-B2 | N-cyclylamides as nematicides | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-16 | — | — | US | disclosed |
| US-20160157485-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
| US-20150045213-A1 | N-CYCLYLAMIDES AS NEMATICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160157485-A1 | 4-MEMBERED RING CARBOXAMIDES USED AS NEMATICIDES | TUBA3C, DDT, CYCS | HTR2A 2168/4885HTR2C 602/4885HTR2B 735/4885 |
| US-20150045213-A1 | N-CYCLYLAMIDES AS NEMATICIDES | TUBA3C, TUBA1C, TUBB3 | HTR2A 3863/4885HTR2C 3245/4885HTR2B 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.