SCHEMBL4258389

SCHEMBL4258389

O=C(O)C[C@H](O)CCc1ccc(F)cc1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MMP12 P39900 11/20 0.68
MMP13 P45452 10/20 0.68
MMP2 P08253 1/20 0.68
MMP9 P14780 1/20 0.68
MMP14 P50281 1/20 0.68
PTGER1 P34995 1/20 0.49
PTGFR P43088 1/20 0.49
FFAR1 O14842 1/20 0.47
DPP4 P27487 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1139516 1.00 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL5613537 0.95 MMP12 (0.77) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4552726 0.90 MMP12 (0.55) MMP12MMP13MMP2MMP9MMP14
SCHEMBL4745347 0.83 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL8333817 0.83 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL687094 0.83 MMP12 (0.80) MMP12MMP13MMP2MMP9MMP14
SCHEMBL3205639 0.82 MMP12 (0.69) MMP12MMP13MMP2MMP9MMP14
SCHEMBL5613511 0.82 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL1139059 0.82 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14
SCHEMBL6460810 0.82 MMP12 (0.68) MMP12MMP13MMP2MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7632618-B2 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2009-12-15 US disclosed
US-20090061498-A1 POLYHYDROXYALKANOATE-CONTAINING STRUCTURE AND MANUFACTURING METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2009-03-05 US disclosed
EP-1254930-B1 Particles for electrophoresis, a production method thereof and a display using the particles CANON KK (JP) 2008-06-18 EP disclosed
CN-100393881-C Polyhydroxyalkanoate-containing structure and method for producing the same CANON KK (JP) 2008-06-11 CN disclosed
EP-1275728-B1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KK (JP) 2008-06-04 EP disclosed
US-7186459-B2 Liposome coated with polyhydroxyalkanoate and production method thereof CANON KABUSHIKI KAISHA (JP) 2007-03-06 US disclosed
CN-1278675-C Granular material comprising polyhydroxyalkanoate and method for producing the same CANON KK (JP) 2006-10-11 CN disclosed
EP-1256606-B1 Pigment containing ink and production method thereof CANON KK (JP) 2006-03-08 EP disclosed
US-6951745-B2 Synthesizing on base material polyhydroxyalkanoate using 3-hydroxyacyl coenzyme A to become substrate of synthase and coating base surface with polyhydroxyalkanoate where synthase contains sequence which binds to base CANON KABUSHIKI KAISHA (JP) 2005-10-04 US disclosed
US-20050208635-A1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2005-09-22 US disclosed
EP-1277464-B1 Liposome coated with polyhydroxyalkanoate and production method thereof CANON KK (JP) 2004-10-06 EP disclosed
CN-1490357-A Polyhydroxyalkanoate-containing structure and method for producing the same ������������ʽ���� 2004-04-21 CN disclosed
US-20030224494-A1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2003-12-04 US disclosed
US-20030206330-A1 Particles for electrophoresis, a production method thereof and a display using the articles CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-20030203987-A1 Pigment containing ink and production method thereof CANON KABUSHIKI KAISHA (JP) 2003-10-30 US disclosed
CN-1431041-A Granular material comprising polyhydroxyalkanoate and method for producing the same CANON KK (JP) 2003-07-23 CN disclosed
US-20030113368-A1 Liposome coated with polyhydroxyalkanoate and production method thereof CANON KABUSHIKI KAISHA (JP) 2003-06-19 US disclosed
EP-1275728-A1 Polyhydroxyalkanoate-containing structure and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2003-01-15 EP disclosed
EP-1256606-A2 Pigment containing ink and production method thereof CANON KABUSHIKI KAISHA (JP) 2002-11-13 EP disclosed
EP-1254930-A2 Particles for electrophoresis, a production method thereof and a display using the particles CANON KABUSHIKI KAISHA (JP) 2002-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113368-A1 Liposome coated with polyhydroxyalkanoate and production method thereof LIPA, ABHD16A, LIPE MMP12 1924/4885MMP13 1623/4885MMP2 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.