Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256708 | 0.86 | CYP2D6 (0.50) | CYP2D6TSHRTP53RECQLADRB2 | |
| SCHEMBL594098 | 0.79 | ADRB2 (0.44) | CYP2D6TSHRADRB2ADRB1CYP1A2 | |
| SCHEMBL30169480 | 0.79 | ADRB2 (0.44) | CYP2D6TSHRADRB2ADRB1CYP1A2 | |
| Levosalbutamol SCHEMBL2588389 | 0.77 | ADRB2 (0.67) | CYP2D6TSHRADRB2ADRB1ADRB3 | |
| Albuterol SCHEMBL3831149 | 0.77 | ADRB2 (0.67) | CYP2D6TSHRADRB2ADRB1ADRB3 | |
| Sulfuric Acid SCHEMBL2524101 | 0.75 | PMP22 (0.50) | CYP2D6TSHRADRB2ADRB1MEN1 | |
| Sulfuric Acid SCHEMBL21825446 | 0.75 | PMP22 (0.50) | CYP2D6TSHRADRB2ADRB1MEN1 | |
| Alcohol SCHEMBL18886336 | 0.69 | TSHR (0.79) | CYP2D6TSHRTP53RECQLMEN1 | |
| Methyl Alcohol SCHEMBL29466887 | 0.69 | TSHR (0.92) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL223030 | 0.68 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488758-B2 | Levalbuterol hydrochloride polymorph B | TEVA PHARMACEUTICAL FINE CHEMICALS, S.R.L. (IT) | 2009-02-10 | — | — | US | disclosed |