Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258634 | 0.86 | CYP2D6 (0.47) | CYP2D6TSHRTP53RECQLADRB2 | |
| Albuterol SCHEMBL3831149 | 0.73 | ADRB2 (0.67) | CYP2D6TSHRADRB2ADRB1ADRB3 | |
| Levosalbutamol SCHEMBL2588389 | 0.73 | ADRB2 (0.67) | CYP2D6TSHRADRB2ADRB1ADRB3 | |
| Alcohol SCHEMBL18886336 | 0.71 | TSHR (0.79) | CYP2D6TSHRTP53RECQLMEN1 | |
| Methyl Alcohol SCHEMBL29466887 | 0.71 | TSHR (0.92) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL670257 | 0.71 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL11886503 | 0.71 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL221678 | 0.71 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL223030 | 0.71 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 | |
| SCHEMBL14117921 | 0.71 | TSHR (1.00) | CYP2D6TSHRTP53RECQLSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482489-B2 | Enantiomerically pure (R)-albuterol dibenzoyltartrate and protected analogs thereof | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2009-01-27 | — | — | US | disclosed |
| US-20080132579-A1 | Preparation of levalbuterol hydrochloride | TEVA PHARMACEUTICALS USA, INC. FOR BARBADOS. | 2008-06-05 | — | — | US | disclosed |
| EP-1641741-A1 | LEVALBUTEROL HYDROCHLORIDE POLYMORPH B | Teva Pharmaceutical Fine Chemicals S.R.L. (IT) | 2006-04-05 | — | — | EP | disclosed |
| US-20050267216-A1 | Levalbuterol hydrochloride polymorph B | TEVA PHARMACEUTICALS USA, INC. | 2005-12-01 | — | — | US | disclosed |
| WO-2005113482-A1 | LEVALBUTEROL HYDROCHLORIDE POLYMORPH B | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.L. (IT) | 2005-12-01 | — | — | WO | disclosed |
| US-20050261368-A1 | Preparation of levalbuterol hydrochloride | TEVA PHARMACEUTICAL FINE CHEMICALS S.R.I. (IT) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132579-A1 | Preparation of levalbuterol hydrochloride | LDHB, DLST, DAGLB | CYP2D6 639/4885TSHR 2097/4885TP53 4804/4885 |
| US-20050261368-A1 | Preparation of levalbuterol hydrochloride | LDHB, DLST, DAGLB | CYP2D6 639/4885TSHR 2097/4885TP53 4804/4885 |
| US-20050267216-A1 | Levalbuterol hydrochloride polymorph B | LDHB, CYP11B1, MYO3B | CYP2D6 108/4885TSHR 3902/4885TP53 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.