Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922689 | 0.87 | LPL (0.40) | LPLLIPGCXCR2DGAT1 | |
| SCHEMBL18343941 | 0.87 | LPL (0.35) | LPLLIPGCXCR2DGAT1 | |
| SCHEMBL30296064 | 0.84 | LPL (0.38) | LPLLIPGCXCR2DGAT1 | |
| SCHEMBL29543244 | 0.81 | CXCR2 (0.40) | LPLLIPGCXCR2 | |
| SCHEMBL23295322 | 0.81 | CXCR2 (0.40) | LPLLIPGCXCR2 | |
| SCHEMBL10213857 | 0.80 | CXCR2 (0.41) | LPLLIPGCXCR2 | |
| SCHEMBL599785 | 0.80 | CA12 (0.30) | — | |
| SCHEMBL24309534 | 0.77 | LPL (0.37) | LPLLIPGCXCR2DGAT1 | |
| SCHEMBL15328636 | 0.77 | DGAT1 (0.45) | LPLLIPGCXCR2DGAT1 | |
| SCHEMBL31163886 | 0.76 | CXCR2 (0.33) | LPLLIPGCXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |