Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL16758814 | 0.88 | KMT2A (0.40) | KMT2ACHEK2CHEK1KCNH2MAPT | |
| SCHEMBL28323285 | 0.83 | SLC6A1 (0.40) | KMT2AMAPTTSHRKDM4EATM | |
| SCHEMBL16759127 | 0.77 | CHRNA7 (0.55) | KMT2A | |
| Trifluoroacetic Acid SCHEMBL16758816 | 0.77 | KMT2A (0.42) | KMT2AMAPTPOLBIRAK4SUCNR1 | |
| Hydrochloric Acid SCHEMBL6621806 | 0.76 | CHRNA7 (0.54) | KMT2A | |
| SCHEMBL5161390 | 0.76 | CHRM2 (0.59) | KCNH2CYP2C19CYP2D6 | |
| SCHEMBL30302228 | 0.73 | HTR1A (0.34) | HTR1ASLC6A2 | |
| SCHEMBL27771638 | 0.73 | CHRNA7 (0.54) | KMT2AMAPT | |
| SCHEMBL3634169 | 0.72 | PARP10 (0.69) | CHEK2KCNH2PARP10 | |
| SCHEMBL16759167 | 0.72 | KMT2A (0.48) | KMT2AMAPTPOLBSUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044055-A2 | AMIDE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008011131-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |