Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 8/20 | 0.34 |
| ▸ | XIAP | P98170 | 8/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569722 | 1.00 | ELANE (0.34) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL8062027 | 0.92 | BIRC2 (0.36) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL8058789 | 0.83 | BIRC2 (0.36) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL8045867 | 0.82 | BIRC2 (0.39) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL8060002 | 0.82 | ELANE (0.39) | ELANE | |
| SCHEMBL4259361 | 0.82 | XIAP (0.33) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL4569723 | 0.82 | XIAP (0.33) | ELANEBIRC2XIAPBIRC3 | |
| SCHEMBL4259244 | 0.81 | ELANE (0.37) | ELANEBIRC2 | |
| SCHEMBL8056938 | 0.81 | VHL (0.33) | ELANE | |
| SCHEMBL8062117 | 0.80 | ELANE (0.32) | ELANEBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |