Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 10/20 | 0.33 |
| ▸ | BIRC3 | Q13489 | 9/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 9/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569723 | 1.00 | XIAP (0.33) | XIAPBIRC3BIRC2ELANE | |
| SCHEMBL4569722 | 0.82 | ELANE (0.34) | XIAPBIRC3BIRC2ELANE | |
| SCHEMBL4259352 | 0.82 | ELANE (0.34) | XIAPBIRC3BIRC2ELANE | |
| SCHEMBL8060002 | 0.81 | ELANE (0.39) | ELANE | |
| SCHEMBL4259244 | 0.81 | ELANE (0.37) | BIRC2ELANE | |
| SCHEMBL8062027 | 0.79 | BIRC2 (0.36) | XIAPBIRC3BIRC2ELANE | |
| SCHEMBL3372356 | 0.77 | — | — | |
| SCHEMBL3370425 | 0.76 | — | — | |
| SCHEMBL8045867 | 0.73 | BIRC2 (0.39) | XIAPBIRC3BIRC2ELANE | |
| SCHEMBL8038455 | 0.73 | ELANE (0.48) | XIAPBIRC2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |