Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 10/20 | 0.39 |
| ▸ | XIAP | P98170 | 10/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 7/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062027 | 0.86 | BIRC2 (0.36) | BIRC2XIAPBIRC3ELANE | |
| SCHEMBL8060002 | 0.83 | ELANE (0.39) | ELANE | |
| SCHEMBL4259244 | 0.83 | ELANE (0.37) | BIRC2ELANE | |
| SCHEMBL4569722 | 0.82 | ELANE (0.34) | BIRC2XIAPBIRC3ELANE | |
| SCHEMBL4259352 | 0.82 | ELANE (0.34) | BIRC2XIAPBIRC3ELANE | |
| SCHEMBL13757912 | 0.78 | CTSB (0.50) | — | |
| SCHEMBL3375616 | 0.78 | — | — | |
| SCHEMBL13757913 | 0.78 | — | — | |
| SCHEMBL3371445 | 0.78 | CTSB (0.50) | — | |
| SCHEMBL8064635 | 0.78 | CYP3A4 (0.42) | BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |