SCHEMBL4259365

SCHEMBL4259365

COc1cc2[nH]c3ccccc3c2cc1Br

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.69
MAPT P10636 2/20 0.69
ATM Q13315 1/20 0.69
ALDH1A1 P00352 2/20 0.56
HSD17B10 Q99714 2/20 0.56
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
HPGD P15428 1/20 0.56
AHR P35869 1/20 0.55
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50
GABRG2 P18507 1/20 0.50
GABRB3 P28472 1/20 0.50
GABRA5 P31644 1/20 0.50
GABRA3 P34903 1/20 0.50
GABRA2 P47869 1/20 0.50
GABRB2 P47870 1/20 0.50
GABRA4 P48169 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31609245 0.88 GRIN2D (0.60) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL4256786 0.88 GRIN2D (0.60) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL15926660 0.86 KDM4E (0.73) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL7983972 0.86 KDM4E (0.77) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL27919444 0.82 MAPT (0.50) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL3502816 0.81 GRIN2D (0.55) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL4143973 0.81 MAPT (1.00) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL30988966 0.80 AHR (0.71) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL5008841 0.80 AHR (0.71) KDM4EMAPTATMALDH1A1HSD17B10
SCHEMBL31744504 0.80 GRIN2D (0.60) KDM4EMAPTATMALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708078-A Organic electroluminescent material and device 环球展览公司 2025-03-28 CN disclosed
CN-113024609-B Organic electroluminescent material and device 环球展览公司 2025-01-14 CN disclosed
CN-113024609-A Organic electroluminescent material and device 环球展览公司 2021-06-25 CN disclosed
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-10 US disclosed
US-20090242876-A1 CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2009-10-01 US disclosed
US-20090242876-A1 CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2009-10-01 US disclosed
US-20090242876-A1 CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2009-10-01 US disclosed
US-20080269461-A1 Polymeric Carbazole Compounds KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-10-30 US disclosed
US-20080269461-A1 Polymeric Carbazole Compounds KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-10-30 US disclosed
US-20080269461-A1 Polymeric Carbazole Compounds KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-10-30 US disclosed
EP-1966270-A1 POLYMERIC CARBAZOLE COMPOUNDS Koninklijke Philips Electronics N.V. (NL) 2008-09-10 EP disclosed
EP-1838671-B1 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS KONINKL PHILIPS ELECTRONICS NV (NL) 2008-06-04 EP disclosed
EP-1838671-A2 9,9'- AND 2,2'-SUBSTITUTED 3,3'-BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS Koninklijke Philips Electronics N.V. (NL) 2007-10-03 EP disclosed
WO-2007072240-A1 POLYMERIC CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed
WO-2007072240-A1 POLYMERIC CARBAZOLE COMPOUNDS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2007-06-28 WO disclosed
WO-2006061759-A2 9 , 9 ' - AND 2 , 2 ' -SUBSTITUTED 3 , 3 ' -BICARBAZOLYL DERIVATIVES FOR USE IN SEMICONDUCTING MATERIALS AS A HOST MATRIX FOR PHOSPHORESCENT EMITTERS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090242876-A1 CARBAZOLE COMPOUNDS CCNI, IL33, PAICS KDM4E 3143/4885MAPT 2051/4885ATM 2694/4885
US-20210175443-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC KDM4E 1544/4885MAPT 1102/4885ATM 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.