Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259755 | 1.00 | KEAP1 (0.32) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL1259243 | 0.77 | — | — | |
| SCHEMBL16865867 | 0.77 | KEAP1 (0.33) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL1259244 | 0.77 | — | — | |
| SCHEMBL4264708 | 0.77 | KEAP1 (0.33) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL4264704 | 0.77 | KEAP1 (0.33) | KEAP1NFE2L2HCAR2 | |
| SCHEMBL23227153 | 0.75 | — | — | |
| SCHEMBL11600180 | 0.71 | OXER1 (0.31) | — | |
| SCHEMBL950272 | 0.71 | CYP2C19 (0.45) | — | |
| SCHEMBL11600489 | 0.71 | OXER1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137822-A1 | Process for preparing 3-substituted thiophene | UBE INDUSTRIES, LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137822-A1 | Process for preparing 3-substituted thiophene | TMT1A, CTH, CBR1 | KEAP1 65/4885NFE2L2 862/4885HCAR2 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.