SCHEMBL4259772

SCHEMBL4259772

Cc1cccc2sc3nc(/C=C4/C(=O)N5C(OC(=O)O)=CS[C@H]45)cn3c12

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4259771 0.86 BRPF1 (0.38) BRPF1
SCHEMBL4259814 0.86 BRPF1 (0.38) BRPF1
SCHEMBL4262075 0.82 PARP15 (0.36)
SCHEMBL4263337 0.79 MAPT (0.36)
SCHEMBL4261702 0.76 NPC1 (0.37)
SCHEMBL4259319 0.76 NPC1 (0.35)
SCHEMBL4256026 0.75 MAP3K5 (0.32)
SCHEMBL9665359 0.73
SCHEMBL4255587 0.73
SCHEMBL9666200 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1499622-B1 HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS WYETH CORP (US) 2009-03-11 EP claimed