Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6000644 | 0.91 | ALDH1A1 (0.41) | L3MBTL1L3MBTL3ALDH1A1TSHRKMT2A | |
| SCHEMBL6948721 | 0.80 | L3MBTL3 (0.53) | L3MBTL1L3MBTL3ALDH1A1KMT2AOPRL1 | |
| SCHEMBL3263017 | 0.78 | L3MBTL3 (0.72) | L3MBTL1L3MBTL3KMT2AOPRL1OPRM1 | |
| SCHEMBL3069120 | 0.78 | L3MBTL3 (0.67) | L3MBTL1L3MBTL3ALDH1A1KMT2AOPRL1 | |
| SCHEMBL3311978 | 0.77 | L3MBTL3 (0.70) | L3MBTL1L3MBTL3KMT2AOPRL1OPRM1 | |
| SCHEMBL6840171 | 0.77 | L3MBTL3 (0.70) | L3MBTL1L3MBTL3KMT2AOPRL1OPRM1 | |
| SCHEMBL5335104 | 0.77 | L3MBTL3 (0.41) | L3MBTL1L3MBTL3ALDH1A1TSHRKMT2A | |
| SCHEMBL5305801 | 0.76 | OPRL1 (0.52) | L3MBTL1L3MBTL3OPRL1OPRM1OPRK1 | |
| SCHEMBL5745494 | 0.74 | CHRM2 (0.66) | L3MBTL1L3MBTL3ALDH1A1TSHRKMT2A | |
| SCHEMBL4257542 | 0.74 | L3MBTL3 (0.53) | L3MBTL1L3MBTL3ALDH1A1KMT2AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-B1 | 3-Heterocyclyl-Azetidine compounds useful as NK1/NK2 receptors antagonists | ALBIREO AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| US-7402581-B2 | Azetidine compounds | ALBIREO AB (SE) | 2008-07-22 | — | — | US | disclosed |
| US-20060172988-A1 | Azetidine compounds | ALBIREO AB (SE) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172988-A1 | Azetidine compounds | HRH2, HRH4, HRH1 | L3MBTL1 4844/4885L3MBTL3 4858/4885ALDH1A1 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.