Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 5/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239409 | 1.00 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL20880792 | 0.82 | GABRA1 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL3801028 | 0.82 | GABRA1 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL1053969 | 0.74 | TSHR (0.55) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL13218794 | 0.70 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL14439671 | 0.70 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL13218812 | 0.70 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL10487817 | 0.69 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL196657 | 0.68 | TSHR (0.50) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL11301017 | 0.67 | TSHR (0.49) | ADRA2AADRA2BADRA2CADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295718-A | Method for preparing medetomidine and derivative thereof | 维科-兹多洛夫希沃特尼赫有限责任公司 | 2023-12-26 | — | — | CN | claimed |
| CN-105792815-B | Composition for treating farsightedness and method | 远视眼治疗有限责任公司 | 2018-08-28 | — | — | CN | disclosed |
| WO-2009052071-A1 | TREATMENT OF SENSORIMOTOR DISORDERS WITH 4- ( 1- ( 2, 3 -DIMETHYLPHENYL) ETHYL) -1H-IMIDAZ0LE-2 ( 3H) -THIONE | ALLERGAN, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009052072-A1 | TREATING MOTOR DISORDERS WITH 4-(1-(2,3-DIMETHYLPHENYL)ETHYL)-1H-IMIDAZOLE-2(3H)-THIONE | ALLERGAN, INC. (US) | 2009-04-23 | — | — | WO | disclosed |